Get the slate

Home › NFL › NFL picks this week › Colts vs Vikings

NFL Week 7 · October 25, 2026, 1:00 PM ET

Colts vs. Vikings Prediction & Preview

Indianapolis Colts at Minnesota Vikings, U.S. Bank Stadium.

Colts vs Vikings prediction

The odds favor the Minnesota Vikings: 73.4% to win (moneyline -325), with the sportsbook's margin removed. The spread is MIN -6.5 and the total 41.5. That is the market's view. Odyn's AI quant model makes its own call before kickoff: unlock the Colts vs Vikings pick free.

Colts vs Vikings preview

Colts vs Vikings sends Indianapolis (2-4) to unbeaten Minnesota (5-0), which is 2-0 at home and 3-0 on the road.

Minnesota's defense is the story: 12.8 points and 282.0 yards allowed per game. Kyler Murray has 662 passing yards with 2 touchdowns and 2 interceptions, Aaron Jones Sr. has 410 rushing yards and Justin Jefferson 258 receiving yards with 3 touchdowns. Nobody is listed as out or questionable for the Vikings; guard Donovan Jackson is on injured reserve.

Indianapolis scores 24.0 points a game but allows 27.3 and 362.8 yards. Jonathan Taylor has 492 rushing yards and 7 touchdowns, Daniel Jones has 1,290 passing yards with 4 touchdowns and 6 interceptions, and Josh Downs leads the receivers with 289 yards. Cornerback Sauce Gardner, tight end Tyler Warren, wide receiver Anthony Gould and linebacker CJ Allen are out; linebacker Bryce Boettcher and cornerback Justin Walley are questionable; wide receiver Alec Pierce is on injured reserve. Odyn's AI quant model runs this game before kickoff, injury report included.

Odyn's pick

Pick drops before kickoff

Will Odyn bet on Colts vs Vikings?

Members get the pick before kickoff, with the odds and the win probability.

+$1,180 at $100 a bet over the last 1,000 NFL games. Every loss counted.

Unlock the Colts vs Vikings pick free

7 days free · then $19.99/month · cancel anytime

Colts vs Vikings spread & over/under

Spread MIN -6.5 · Over/under 41.5

Lines move until kickoff.

Win probability from the odds

Colts 26.6% · Vikings 73.4%

From the moneyline (Colts +260, Vikings -325) with the sportsbook's margin removed. Odds move until kickoff. Check any line with the no-vig calculator, or price a multi-game ticket with the parlay calculator.

That's the sportsbook's view. Odyn's AI quant model makes its own call: members see whether it bets Colts vs Vikings, with its win probability. Unlock the pick free for 7 days

How to watch Colts vs Vikings

Colts vs Vikings: team stats & injury report

Indianapolis Colts

Record2-4
Home1-2
Road1-2
Points per game24.0
Points allowed per game27.3
Yards per game326.5
Passing yards per game215.0
Rushing yards per game111.5
  • Passing: Daniel Jones (130/218, 1290 YDS, 4 TD, 6 INT)
  • Rushing: Jonathan Taylor (122 CAR, 492 YDS, 7 TD)
  • Receiving: Josh Downs (24 REC, 289 YDS)

Injury report: Anthony Gould (WR, Out); CJ Allen (LB, Out); Sauce Gardner (CB, Out); Tyler Warren (TE, Out); Bryce Boettcher (LB, Questionable); Justin Walley (CB, Questionable); Alec Pierce (WR, Injured Reserve)

Minnesota Vikings

Record5-0
Home2-0
Road3-0
Points per game21.8
Points allowed per game12.8
Yards per game303.6
Passing yards per game187.6
Rushing yards per game116.0
  • Passing: Kyler Murray (69/101, 662 YDS, 2 TD, 2 INT)
  • Rushing: Aaron Jones Sr. (97 CAR, 410 YDS, 2 TD)
  • Receiving: Justin Jefferson (19 REC, 258 YDS, 3 TD)

Injury report: Donovan Jackson (G, Injured Reserve)

Injury reports: Colts · Vikings · every NFL team · how the odds moved: NFL line movement.

Unlock today's bets

Members see every pick, its odds and win probability

Try it free for 7 days

7 days free · then $19.99/month · cancel anytime

Updated Oct 25, 06:25 PM ET.

By the Odyn Team · 21+ · Gambling problem? Call 1-800-GAMBLER · Responsible gambling