Buccaneers vs. Panthers Prediction & Preview

Tampa Bay Buccaneers at Carolina Panthers, Bank of America Stadium.

Buccaneers vs Panthers prediction

The odds favor the Carolina Panthers: 59.3% to win (moneyline -162), with the sportsbook's margin removed. The spread is CAR -3 and the total 44.5. That is the market's view. Odyn's AI quant model makes its own call before kickoff: unlock the Buccaneers vs Panthers pick free.

Buccaneers vs Panthers preview

Buccaneers vs Panthers puts Tampa Bay (1-5) in Carolina (3-2). The Buccaneers are 0-4 at home and 1-1 on the road; the Panthers are 1-1 at home.

Quarterback Baker Mayfield is questionable for Tampa Bay; he has 615 passing yards with 2 touchdowns and 2 interceptions. Bucky Irving has 452 rushing yards and Chris Godwin Jr. leads the receivers with 216 yards. Wide receiver Emeka Egbuka, safety Antoine Winfield Jr. and tackle Luke Goedeke are out, and linebacker Christian Rozeboom is on injured reserve. The Buccaneers score 19.8 points and allow 23.0 a game.

Carolina has the passing game: 309.8 passing yards and 29.2 points per game. Bryce Young has 1,549 yards with 11 touchdowns and 2 interceptions, Tetairoa McMillan has 471 receiving yards and Chuba Hubbard 426 rushing yards. Linebacker Jaelan Phillips is out, tackle Monroe Freeling is questionable, and running back Jonathon Brooks, defensive tackle Cam Jackson and linebacker Thomas Incoom are on injured reserve. Odyn's AI quant model runs this game before kickoff, injury report included.

Odyn's pick

Pick drops before kickoff

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Buccaneers vs Panthers spread & over/under

Spread CAR -3 · Over/under 44.5

Lines move until kickoff.

Win probability from the odds

Buccaneers 40.7% · Panthers 59.3%

From the moneyline (Buccaneers +136, Panthers -162) with the sportsbook's margin removed. Odds move until kickoff. Check any line with the no-vig calculator, or price a multi-game ticket with the parlay calculator.

That's the sportsbook's view. Odyn's AI quant model makes its own call: members see whether it bets Buccaneers vs Panthers, with its win probability. Unlock the pick free for 7 days

How to watch Buccaneers vs Panthers

Date: Sunday, October 25, 2026
Time: 1:00 PM ET
Venue: Bank of America Stadium
TV: Fox

Buccaneers vs Panthers: team stats & injury report

Tampa Bay Buccaneers

Record	1-5
Home	0-4
Road	1-1
Points per game	19.8
Points allowed per game	23.0
Yards per game	313.8
Passing yards per game	186.0
Rushing yards per game	127.8

Passing: Baker Mayfield (61/96, 615 YDS, 2 TD, 2 INT)
Rushing: Bucky Irving (96 CAR, 452 YDS, 2 TD)
Receiving: Chris Godwin Jr. (23 REC, 216 YDS)

Injury report: Antoine Winfield Jr. (S, Out); Emeka Egbuka (WR, Out); Luke Goedeke (OT, Out); Baker Mayfield (QB, Questionable); Christian Rozeboom (LB, Injured Reserve)

Carolina Panthers

Record	3-2
Home	1-1
Road	2-1
Points per game	29.2
Points allowed per game	24.6
Yards per game	418.6
Passing yards per game	309.8
Rushing yards per game	108.8

Passing: Bryce Young (121/201, 1549 YDS, 11 TD, 2 INT)
Rushing: Chuba Hubbard (89 CAR, 426 YDS, 4 TD)
Receiving: Tetairoa McMillan (32 REC, 471 YDS, 2 TD)

Injury report: Jaelan Phillips (LB, Out); Monroe Freeling (OT, Questionable); Cam Jackson (DT, Injured Reserve); Jonathon Brooks (RB, Injured Reserve); Thomas Incoom (LB, Injured Reserve)

Injury reports: Buccaneers · Panthers · every NFL team · how the odds moved: NFL line movement.

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Updated Oct 25, 06:25 PM ET.

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