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NBA · October 25, 2026, 7:30 PM ET

Pistons vs. 76ers Prediction & Preview

Detroit Pistons at Philadelphia 76ers, Xfinity Mobile Arena.

Pistons vs 76ers prediction

The odds favor the Philadelphia 76ers: 50.4% to win (moneyline -112), with the sportsbook's margin removed. The spread is PHI -1.5 and the total 227.5. That is the market's view. Odyn's AI quant model makes its own call before tip-off: unlock the Pistons vs 76ers pick free.

Pistons vs 76ers preview

Pistons vs 76ers sends 2-0 Detroit to 3-0 Philadelphia at Xfinity Mobile Arena, Sunday, October 25 at 7:30 PM ET. The 76ers play the second night of a back-to-back after hosting Milwaukee on Saturday.

Detroit, the No. 1 seed in the East last season at 60-22, opened with a 121-113 home win over Boston on October 20 and a 128-111 win at Miami on October 23. The Pistons score 124.5 points a game and allow 112.0. Duncan Robinson leads them with 19.0 points a game, Paul Reed has 8.5 rebounds and Cade Cunningham 8.0 assists. Last season Detroit scored 117.8 points a game and allowed 109.6. Center Jalen Duren is out; guard Ausar Thompson is day-to-day.

Philadelphia won 106-100 at New York on October 20, 114-106 at home against Cleveland on October 22 and 127-116 against Milwaukee on October 24. The 76ers score 115.7 points a game and allow 107.3. Tyrese Maxey leads them with 28.7 points a game, and Joel Embiid has 9.7 rebounds and 5.7 assists. Last season Philadelphia went 45-37 as the No. 7 seed in the East, scoring 115.9 and allowing 116.1. Centers Ariel Hukporti and Tacko Fall and forwards Dominick Barlow and LeBron James are out; Embiid and forward Jabari Walker are day-to-day. Odyn's AI quant model runs this game before tip-off, injury report included.

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Pistons vs 76ers spread & over/under

Spread PHI -1.5 · Over/under 227.5

Lines move until tip-off.

Win probability from the odds

Pistons 49.6% · 76ers 50.4%

From the moneyline (Pistons -108, 76ers -112) with the sportsbook's margin removed. Odds move until tip-off. Check any line with the no-vig calculator, or price a multi-game ticket with the parlay calculator.

That's the sportsbook's view. Odyn's AI quant model makes its own call: members see whether it bets Pistons vs 76ers, with its win probability. Unlock the pick free for 7 days

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Pistons vs 76ers: team stats & injury report

Detroit Pistons

Record2-0
Home1-0
Road1-0
Points per game124.5
Points allowed per game112.0

Last season (2025-26: 60-22, 117.8 points per game, 109.6 allowed, No. 1 seed in the East)

Team leaders

  • Points per game: Duncan Robinson (19.0)
  • Rebounds per game: Paul Reed (8.5)
  • Assists per game: Cade Cunningham (8.0)

Last 5 games played (preseason and playoffs included):

  • 10/23 @ Miami Heat: W 128-111
  • 10/20 vs Boston Celtics: W 121-113
  • 10/16 vs Toronto Raptors: W 129-125
  • 10/14 @ Minnesota Timberwolves: W 128-106
  • 10/10 @ Washington Wizards: L 114-108 OT

Injury report: Jalen Duren (C, Out); Ausar Thompson (G, Day-To-Day)

Philadelphia 76ers

Record3-0
Home2-0
Road1-0
Points per game115.7
Points allowed per game107.3

Last season (2025-26: 45-37, 115.9 points per game, 116.1 allowed, No. 7 seed in the East)

Team leaders

  • Points per game: Tyrese Maxey (28.7)
  • Rebounds per game: Joel Embiid (9.7)
  • Assists per game: Joel Embiid (5.7)

Last 5 games played (preseason and playoffs included):

  • 10/24 vs Milwaukee Bucks: W 127-116
  • 10/22 vs Cleveland Cavaliers: W 114-106
  • 10/20 @ New York Knicks: W 106-100
  • 10/16 vs Boston Celtics: L 125-120 OT
  • 10/10 @ Boston Celtics: L 144-106

Injury report: Ariel Hukporti (C, Out); Dominick Barlow (F, Out); LeBron James (F, Out); Tacko Fall (C, Out); Jabari Walker (F, Day-To-Day); Joel Embiid (C, Day-To-Day)

Injury reports: Pistons · 76ers · every NBA team · how the odds moved: NBA line movement.

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Updated Oct 25, 06:25 PM ET.

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